A Sanford woman was killed Friday, April 11, when her car was hit by a truck on U.S. 421, according to the NC Highway Patrol. The crash happened about 6 a.m. at the Cox Mill Road intersection, Trooper ...

Officials said two lanes of U.S. 421 are closed near Kernersville. The lanes are closed past exit 224. Sign up for our ...

A man is facing several charges after a 100 mph wrong-way chase on US 421, according to the Wilkesboro Police Department. At ...

You might need to rethink your travel plans if you're driving through the western part of the Piedmont Triad tomorrow.Crews ...

Traffic along U.S. 421 in the Boone Mountain area should be mitigated moving forward, according to Watauga County Emergency ...

Since opening in 2020, 421 Creamery has hand-scooped over 200,000 ice-cream dips, blended 35,000 shakes and crafted 11,000 ...