With increasing numbers of short hairpin RNA (shRNA) and short interfering RNA (siRNA) libraries available to researchers along with new systematic and pooled screening approaches, RNAi screens in ...

Multiparametric imaging of siRNA screening data sheds light on endocytosis. Endocytosis allows eukaryotic cells to remove signaling receptors from their surfaces and to take up extracellular ...

Novel small interfering RNA (siRNA) agent lepodisiran drastically cut levels of lipoprotein(a), or Lp(a), in the phase II ALPACA trial. The 400-mg dose cut Lp(a) by 93.9 percentage points compared ...

The siRNA molecules bind to special protein complexes and guide ... The team has also optimized the process of screening for efficient siRNAs and can adapt the procedure to target new viral mutations ...