BMO Capital Markets analysts said the results potentially position lepodisiran as “one of the most durable assets in ...

Specifically, one strand of a double-stranded siRNA molecule can be incorporated into a complex called RISC. This RNA-containing complex can then inhibit transcription of an mRNA molecule that has ...

Whereas siRNA and shRNA molecules can be obtained quickly and reasonably affordably, the generation of small-molecule inhibitors for specific proteins requires a more substantial investment.

Targeting can be achieved by directly conjugating the siRNA molecule with a small molecule that specifically binds to the cell of interest, or by attaching a targeting molecule such as an antibody ...

In this study, the authors demonstrated that exosomes can serve as delivery vehicles to introduce AGO2-loaded siRNA into the cytoplasm of bacteria, and in turn down-regulated gene expression of ...

Codexis shares were 20% higher, at $3.07, after the company recorded its first revenue-generating contract to manufacture siRNA material in its ECO Synthesis Innovation Lab.

Details of each trial can be found on www.clinicaltrials.gov. † Ongoing trials. AMD: Age-related macular degeneration; DME: Diabetic macular edema; iv.: Intravenous ...

In this study, the authors demonstrated that exosomes can serve as delivery vehicles to introduce AGO2-loaded siRNA into the cytoplasm of bacteria, and in turn down-regulated gene expression of ...