The double-stranded RNA is processed by an RNase III family enzyme Dicer, resulting in the generation of an siRNA, a 21–23-nucleotide (nt) RNA duplex, composed of a 19-mer sequence with ...

Given the growing antibiotic resistance crisis, novel ways to target bacterial infections are becoming increasingly important. One potential strategy is to manipulate bacterial genes at the ...

The success of COVID-19 vaccines has highlighted the potential of mRNA-based therapies, which selectively manipulate how genes relay a function ... of both mRNA and siRNA in vivo and in vitro ...

RVG–9R might not only be a highly promising drug delivery system for siRNA and potentially other therapeutic molecules, but also a powerful tool to systematically analyse gene function in the ...