Additional features: shRNA expression cassette under the control of H1 pol III promoter, a PGK-puromycin marker and ampicillin-resistance marker for selection. Library stability. Recombination may ...

Shortly after the cellular mechanism of RNA interference (RNAi) was first described, scientists began utilizing this powerful technique to study gene function. The most effective way to alter a gene’s ...

Here we used parallel genome-wide high-coverage short hairpin RNA (shRNA) and clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 screens to identify the cellular target and ...

Firm gains shRNA libraries for human and mouse genomes. Thermo Fisher Scientific is acquiring Open Biosystems to expand its position in the RNAi field. Open Biosystems specializes in shRNA and ...