Mitochondrial DNA sequence data has proved extremely useful ... Currently, it is difficult to predict the way in which mtDNA mutations will pass from mother to child due to the interplay between ...

The other approach analyzes mitochondrial DNA, or mtDNA. Because mtDNA tends to survive long after nuclear DNA has disintegrated, this approach is useful in identifying the remains of persons who ...

The novel framework—described in the journal Nature—provides geneticists with a long-needed tool to determine which ...

Researchers at the University of Gothenburg have identified a small molecule, PZL-A, that restores function in the defective POLG enzyme, critical for mitochondrial DNA replication. The compound has ...

But were these truly the remains of the Romanov family? To confirm their identities, researchers turned to mitochondrial DNA (mtDNA), which passes unchanged from mother to child. They obtained blood ...

Typically, humans inherit mitochondria and mitochondrial DNA from their mothers only. But using sequencing data from the mitochondrial genomes of members from three unrelated families, researchers ...

Damage to the genetic material of mitochondria—the mitochondrial DNA or mtDNA for short—can lead to diseases such as Parkinson's, Alzheimer's, amyotrophic lateral sclerosis (ALS ...

When the mechanisms that replicate or repair mitochondrial DNA (mtDNA) fail, it can cause a wide range of syndromes for which there are few to zero existing treatment options. One of the causes of ...

Caption The graphic shows images of a cell under mtDNA replication stress made using so-called Correlative Light and Electron Microscopy (for short: CLEM). The mitochondrial DNA (mtDNA, green) is ...

The graphic shows images of a cell under mtDNA replication stress made using so-called Correlative Light and Electron Microscopy (for short: CLEM). The mitochondrial DNA (mtDNA, green) is ejected ...