causing them to release mitochondrial DNA (mtDNA) into the cytosol. This triggers the cGAS-STING pathway, a major immune ...

The other approach analyzes mitochondrial DNA, or mtDNA. Because mtDNA tends to survive long after nuclear DNA has disintegrated, this approach is useful in identifying the remains of persons who ...

The graphic shows images of a cell under mtDNA replication stress made using so-called Correlative Light and Electron Microscopy (for short: CLEM). The mitochondrial DNA (mtDNA, green) is ejected ...