This paper describes the alterations and mechanisms that are involved in microRNA (miRNA) dysregulation in human cancer and how such dysregulation is involved in cancer initiation and progression.

Victor Ambros and Gary Ruvkun won this year’s Physiology or Medicine award for the discovery of microRNA and its role in post-transcriptional gene regulation. Danielle is a Senior Editor at The ...

Recent studies have introduced a paradigm shift in our understanding of the microRNA biogenesis pathway, which was previously believed to be universal to all microRNAs. Maturation steps specific ...

PROSTOX predicts late genitourinary toxicity, yielding area under the curve of 0.76. (HealthDay News) — A biomarker consisting primarily of microRNA-based germline biomarkers (mirSNPs), PROSTOX ...

The origin of their recognition comes from a pair of studies published in the journal Cell way back in 1993, which demonstrated for the first time that microRNA was involved in gene regulation in ...

Particularly microRNAs have emerged as informative biomarkers of cell status and function. Sensitive, specific and unbiased microRNA profiling in liquid biopsies – from serum and plasma, to urine and ...

One author disclosed ties to MiraDx, which licensed intellectual property from Yale University surrounding microRNA-binding site variants.