They identified the mechanistic target of rapamycin complex 1 (mTORC1) pathway as a highly used system. Then the researchers developed a conditional mutant mouse model with a deleted upstream mTORC1 ...

They looked at the ability of omega-6 fatty acids -- particularly linoleic acid, the dominant one in the Western diet -- to drive an important, nutrient-sensing growth pathway called the mTORC1 ...

Researchers discovered that an essential fatty acid called omega-6 linoleic acid, which we can only get by eating it, directly activates a central growth pathway in our cells called mTORC1.

Their research revealed linoleic acid can activate mTORC1 — the 'control center' in cells that decides whether they grow, divide or make proteins. In aggressive breast cancer, excess linoleic ...

They looked at the ability of omega-6 fatty acids-particularly linoleic acid, the dominant one in the Western diet-to drive an important, nutrient-sensing growth pathway called the mTORC1 pathway.

A major player in this balancing act is a cellular signaling network called mTORC1. It acts like a sensor and regulator, helping cells grow when nutrients are available. This pathway is especially ...