Cre is a type of DNA recombination enzyme that binds to a short DNA sequence (loxP) of 34 base pairs and causes site-specific recombination. For example, by inserting a DNA sequence between two ...

When Cre recombinase (red circle) is introduced, either as a transgene by crossing into a mouse line carrying the targeted gene locus or on a viral vector, the DNA between the loxP sites (red ...