Joe Mixon is listed as doubtful to play after missing practice all week with an ankle injury. Dameon Pierce has been ruled out with a hamstring injury and the two injuries leave Houston thin in the backfield for the matchup of 2-0 teams. Cam Akers and Dare Ogunbowale are the other backs on the team’s 53-man roster.

The former Pro Bowler with the Bengals was fairly quiet in Week 2 and now has an ankle injury that will keep him off the field. Pierce, the Texans' RB2, has only three carries this year but went over 1,

What does the Texans' running back room look like with Joe Mixon potentially missing time? Here is a look at the position's depth chart in Houston.