FcRn protects IgG and albumin from catabolism, transports IgG across the placenta, and regulates IgG function. Blocking or augmenting FcRn can decrease autoimmune antibodies and enhance drug ...

Roivant Sciences secures $5.2B for advancing late-stage drugs like IMVT-1402 & brepocitinib. Click here to read an analysis ...

Previous studies established defective Fc receptor mediated clearance in patients with systemic lupus erythematosis (SLE), a disorder associated with circulating immune complexes (CIC).

The US Food and Drug Administration (FDA) has approved an investigational new drug (IND) application from Aclaris ...

The Dutch biotech company said the product was the first and only neonatal Fc receptor blocker approved to treat the condition. The product is co-formulated with Halozyme Therapeutics’ (HALO ...

Health system pharmacists and physicians are monitoring a wave of expected new drug approvals between late 2024 and third quarter of 2025. A recent article published in the American Journal of ...

Here we describe a mouse Fc receptor, designated Fcα/μR, and its human homolog, that bind both IgM and IgA with intermediate or high affinity. Fcα/μR is constitutively expressed on the ...

Viridian Therapeutics, Inc.’s VRDN share price has surged by 5.71%, which has investors questioning if this is right time to ...

After proper training on subcutaneous injection technique, the prefilled syringe may be administered by the patient or caregiver.

This study presents a valuable finding on the direct cytotoxic effects of DuoHexaBody-CD37 in diffuse large B-cell lymphoma, mediated via SHP-1 activation and antibody clustering, independent of ...