A common malaria drug could be repurposed to treat a variety of hematologic cancers and solid tumors, according to early ...

Cancer patients invariably develop resistance to targeted drugs, so drugmakers develop strategies to combat it before ...

Cogent Biosciences (COGT) announced preclinical data from four pipeline programs during poster sessions at the American Association for Cancer ...

Clinicaltrials.gov identifier. RAF, PI3K and the RAL guanine exchange factor (RAL-GEF) were initially identified as essential components of RAS-mediated transformation in rodent cells. Human cell ...

For example, patients diagnosed with non-small cell lung cancer (NSCLC) often receive genomic testing for mutations in genes like KRAS, EGFR and ALK ... role in treatment. PI3K pathway mutations ...