CD3E, along with CD3-gamma, CD3-delta ... CD3E plays a critical role in T-cell development, and mutations in the CD3E gene can lead to severe immunodeficiency. Additionally, CD3E has been linked ...

Intranasal administration of the anti-CD3 mAb to mice immediately (within ... encoded by immune responsive gene 1) and is a key metabolic regulator in immune cells, including microglia.

CD20 × CD3 bispecific antibodies bind to both CD20 on malignant B cells and CD3 on T cells, bringing them into close proximity, which triggers T cell-mediated killing of the targeted B cells.

PsiOxus Therapeutics aims to be the world’s leading cancer gene therapy company to deliver ... fragment specific for the T cell receptor CD3 protein. When expressed together on the surface ...