Organoids are made to model human organs and are promising for research and therapy, but there are limitations in their growth and function. A recent study by researchers at The University of Tokyo ...

CC chemokine receptor 6 (CCR6) is a G-protein coupled receptor involved in guiding immune cells through the body and the hallmark receptor for T helper 17 (Th17) cells, and is also expressed in other ...

A recent study found that placenta-derived IL1α under hypoxic conditions, can greatly increase growth of human stem cell-derived liver organoids. This method offers a promising route to improve ...

In this study, we have shown that the absolute number of Th17 cells using the CCR6 and CD161 markers were significantly higher in the intestinal mucosa of patients with aGVHD compared with ...

To explore the underlying mechanisms, the team performed single-cell RNA sequencing analysis, which revealed that IL1α influences hepatoblast expansion through the SAA1-TLR2-CCL20-CCR6 signaling ...

To explore the underlying mechanisms, the team performed single-cell RNA sequencing analysis, which revealed that IL1α influences hepatoblast expansion through the SAA1-TLR2-CCL20-CCR6 signaling ...