The treatment of asthma and allergic rhinitis using unique, humanized anti-IgE monoclonal antibodies with very particular binding specificities is now supported by the results of multiple phase II ...

Methods: MEDLINE, In-Process & Other Non-Indexed Citations, and EMBASE Drugs & Pharmacology were searched using olizumab, omalizumab, E25, rhuMAb-E25, and anti-IgE. Combinations of rhinitis ...

Around 20% of breast and ovarian cancers express the marker, HER2. By generating anti-HER2 IgE antibodies equivalent to the clinically used IgGs, for the first time we demonstrate that IgEs ...

In vivo studies performed in mouse models demonstrate that an IgE protease achieved comparable efficacy to an approved anti-IgE therapy in animal models of anaphylaxis and allergy, including ...

1 A clinical history of gastrointestinal, skin or respiratory symptoms suggestive of allergy frequently results in allergen-specific IgE testing. The IMMULITE ® 2000/2000 XPi 3gAllergy ...

In vitro, omalizumab and human IgE form several immune complexes that vary in size as the 2 components' molar ratios are changed. [29] The largest complex, a stable cyclical hexameric structure ...