First, we encountered difficulty obtaining the aPTT reagent used at the time, and the alternative aPTT reagent had a large deviation from the previous therapeutic range of 60–90 seconds.

This assay is readily available and inexpensive. However aPTT reagents are poorly standardized and have different sensitivities to heparin. There is no dose response relationship with heparin. Due to ...

the APTT reagent sensitivity and instrumentation. The anti-Xa assay may be affected by hyperbilirubinemia, hyperlipidemia (can be cleared by ultracentrifugation) and decreased anti-thrombin levels ...

aPTT, Fibrinogen and clotting factors. Automatic start when sample and reagent are mixed together in the cuvette. It has 37°C incubator with 18 samples capacity. PT data are printed with RATIO ...

Background: Both the activated partial thromboplastin time (aPTT) and anti-Xa assay can be used to monitor unfractionated heparin (UFH). Following implementation of an anti-Xa method for heparin ...