Our research interests are in the areas of structure determination of biological nano-machines by electron cryo-microscopy (cryo-EM) techniques and computer reconstruction, and the use of structures ...

The Wang Lab first uses electron cryo-microscopy (Cryo-EM) to determine the structural architecture of DNA-bound ER-alpha, SRC-3, and a secondary coactivator (p300) complex. This work provides a ...

Wan B, Guan D, Li S, Chwat-Edelstein T, Zhao X. Mms22-Rtt107 axis attenuates the DNA damage checkpoint and the stability of the Rad9 checkpoint mediator. Nat Commun. 2025 Jan 2;16:311. Li Q, Zhang J, ...