Researchers explore how merging X-ray imaging and cryo-EM could enable real-time, high-resolution views of biology, advancing molecular films and drug design.

Gabe Lander and Adrian Koh talk all things cryo-EM and its pivotal role in structural biology research in this feature.

This Review describes sample preparation strategies for time-resolved methods in structural biology, with a focus on cryo-EM and X-ray crystallography, including opportunities for cross ...

Using cryo-electron microscopy (cryo-EM), a team of structural and molecular biologists at Memorial Sloan Kettering Cancer ...

The Structural Biology Core provides services, training, and support to investigators who utilize X-ray crystallography and cryo-electron microscopy (Cryo-EM) as a tool to address their research ...

Muscle contraction requires a tight communication between Ca2+-permeable ion channels located in the plasma membrane (e.g., L-type calcium channels (CaVs)) and in the sarcoplasmic reticulum (e.g., ...

Monkeypox, caused by the monkeypox virus—a close cousin of smallpox—has spread rapidly worldwide. From 2022 to 2025, more ...

The Cryo-Electron Microscopy Facility (CEMF) advances the overall UAB mission by supporting the application of cryo-EM in making new scientific discoveries. We provide access and training in the use ...

This study reports two cryo-EM structures of the Nipah virus (NiV) polymerase L-P complex in its full-length and truncated ...

Traditional techniques like X-ray crystallography and fiber diffraction provided valuable insights but struggled to capture the complexity of collagen packing in intricate assemblies. Cryo-EM has ...