Figure 3: WNT7A and PAX6 are essential for maintenance of cornea cell fate. Wnt molecules are secreted signalling proteins that have a critical role in controlling cell fate decisions and tissue ...

Wnt7a signals through its receptor Fzd7 to activate the planar-cell-polarity pathway and drive the symmetric expansion of satellite stem cells resulting in enhanced repair of skeletal muscle.

Dr. Rudnicki and his team discovered the exosome-targeting postal code or zip code within a protein called Wnt7a, which plays a critical role in development, growth, regeneration and cancer.

The new study focused on Wnt7a, a protein essential for development, growth, regeneration, and cancer. “Researchers have been trying for years to turn Wnt7a into a muscle regeneration drug ...

Winn and his colleagues investigated a signaling molecule, a protein called Wnt7a, in mice. Several Wnt signaling proteins and the pathways they activate are known to be involved in the ...

It opens the door to a whole new field of drug development.” Dr. Rudnicki and his team discovered the exosome-targeting postal code or zip code within a protein called Wnt7a, which plays a critical ...

First, they showed that Wnt7a can attach itself to exosomes. Then, they deleted various parts of the Wnt7a protein until they found the smallest part that was responsible for exosome-targeting.

Fate Therapeutics, a private, venture backed biopharmaceutical company engaged in the discovery and development of adult stem cell modulators, presented pre-clinical data from its WNT7a protein ...