The recent global monkeypox (mpox) outbreak, with a new and aggressive variant, has underscored the dire need for safe, broadly effective, and accessible vaccines. The LC16m8 vaccine, an attenuated ...

Researchers have employed a cross-species immunological analysis to provide new insights into a smallpox vaccine's ...

Variola is a member of the Poxvirus family of viruses. A close relative of variola within the Poxvirus family, called vaccinia, does not cause smallpox and is used as a vaccine for smallpox (in fact, ...

Vaccinia virus (VACV) confers cross-protective immunity against the variola virus, the causative agent of smallpox, and has therefore been extensively exploited as a preventive vaccine.

Pancreatic cancer is one of the deadliest malignancies, with a 5-year overall survival rate of only 13%. Earlier studies demonstrated that the Lister strain of oncolytic vaccinia virus (VVL) is ...