The biological effects of VEGF are extremely dose-dependent. Loss of even a single allele results in fatal vascular defects in the embryo 2,3, whereas insufficient levels of VEGF or its VEGF 164 ...

Nuclear factor of activated T cells (NFAT) is a family of closely related transcription factors that are ubiquitously expressed in mammalian cells and tissues. NFAT1–4 are regulated by the ...