Nanobody inhibits metastasis of breast tumor cells to lung in mice
A new research paper was published in Oncotarget titled, "A nanobody against the V-ATPase c subunit inhibits metastasis of ...
Baylor College of Medicine2y
TFEB and V-ATPase-mediated Lysosomal Stress Sensing Pathway in Tauopathy
TFEB targets only the aberrant tau species and this specificity may be conferred by a unique tau-induced V-ATPase-mediated TFEB stress sensing and signaling program. This project is to determine TFEB ...
Understanding the cellular mechanisms of obesity-induced inflammation and metabolic dysfunction
Remarkably, the researchers unveiled that this protein inhibits a pump (V-ATPase) present in lysosomes, which harbor various ...