Credit: Kateryna Kon/Science Photo Library/ What is DNA, and how does it work? You don't need a degree in ...

RNA-based therapies, such as small interfering RNA (siRNA) and antisense oligonucleotide (ASOs), rely on the specific base-pairing properties of uracil to target and regulate disease-related genes. In ...

In RNA, however, a base called uracil (U) replaces thymine (T) as the complementary nucleotide to adenine (Figure 3). This means that during elongation, the presence of adenine in the DNA template ...

In this type of pairing, adenine (A) forms two hydrogen bonds with thymine (T) in DNA or uracil (U) in RNA, while guanine (G) forms three hydrogen bonds with cytosine (C). These base pairs are highly ...

Lyttle and Petering 1,2 synthesized 5-bis-(2-chloroethyl)-aminouracil, uracil mustard, or NSC-34462 or U-8344 (Fig. 2), replacing the methyl group of nitrogen mustard with a physiologically active ...

How can just four nitrogenous bases--adenine, cytosine, guanine, and uracil--possibly code for all 20 amino acids? Thus, early researchers quickly determined that the smallest combination of As ...

Nicholas Hud holds up Uracil, on the right, a nucleobase of RNA. Barbituric acid, on the left, looks very much like it and could have been part of a proto-RNA that preceded RNA. Disclaimer ...