To maintain homeostasis, intestinal epithelial cells (IECs) must efficiently manage protein production and secretion, a ...

The protein folding machinery of the endoplasmic reticulum is coupled to the burden of unfolded proteins by an unfolded protein response (UPR) that promotes rectifying transcriptional and ...

This persistent BiP inactivation leads to the buildup of unfolded proteins inside cells, chronically activating the UPR. To determine how mutated FicD causes neonatal diabetes, Drs. Casey and Orth ...

Research and Teaching Interests: Plant Molecular Biology, Endoplasmic Reticulum Stress and Unfolded Protein Response (UPR), Pro- and Anti-apoptotic Signaling in Plant Immunity, Plant Hormonal ...

Over the past 10 days, President Trump introduced tariffs on imports from nearly every country on the planet, then watched markets enter a tailspin, and then earlier this week, he abruptly lowered ...