Although some causes of Angelman syndrome are not known, the most common cause is when the gene known as UBE3A is either missing or not working properly. A gene is a single unit of genetic ...

Lucas Oon has Angelman syndrome, which is characterised by a happy demeanour and an easily excitable nature. Read more at ...

The disorder principally affects the central nervous system, meaning the brain and spinal cord, and it's caused by mutations in the UBE3A gene. This gene carries instructions for a protein needed ...

Angelman syndrome is caused by several genetic mutations, but the most significant is loss of function in the maternally inherited form of the UBE3A gene, which leads to complications in the ...

in the UBE3A gene inherited from the mother. The condition can also be caused by inheritance of two normal copies of UBE3A from the father, with no copy inherited from the mother. Other AS ...

"We are excited to collaborate with TransformaTx Biotherapeutics and FAST to advance this investigational gene therapy into clinical trials and bring more trial opportunities to those living with ...

SINGAPORE – Laughter fills the consultation room whenever Lucas Oon, 17, is with the team managing his care – pediatric neurologist Jeremy Lin, assistant nurse clinician Kimberly Quek and ...