Circadian rhythms are endogenous time-keeping mechanisms that regulate physiological processes in response to external ...

Since the application of molecular biology in cancer biology, lung cancer research has classically focused on molecular drivers of disease. One such pathway, the hypoxic response pathway, is ...

The Wistar Institute's Paul M. Lieberman, Ph.D. and lab identified and tested a new method for targeting certain cancers ...

Cellular senescence (CS) marks a crucial cell cycle halt triggered in proliferating cells under various stress conditions, manifesting across different ...

Circadian rhythms are endogenous time-keeping mechanisms that regulate physiological processes in response to external light-dark cycles. These ...

Since these ES cells contain the exon 11 deletion found in mice that conditionally develop mammary gland tumors, the homologous repair defect is, thus far, found to correlate with tumorigenesis.

This study explores the potential of oncomicrobial vaccines in mitigating tumor progression by targeting specific ...

Genetic mutations in FGFR2 drive tumorigenesis, particularly in endometrial cancer, but Ding’s evidence shows that epigenetic modifications similarly promote oncogenesis. “We’re very excited about ...

In addition to understanding the molecular aberrations behind gastrointestinal tumorigenesis, our ultimate goal is to identify novel diagnostic biomarkers and therapy targets. Besides gene and protein ...