Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an oestrogen independent manner. Targeting vimentin and/or the long ...

Immunotherapy, which uses programmed immune cells to selectively destroy cancer cells, has transformed cancer treatment.

Mitochondria, the powerhouse of the cell, plays a crucial role in reshaping the metabolic reprogramming of cancer cells and TILs.

The immune system plays a key role in detecting and destroying cancer cells. Cancer immunotherapy works by programming immune cells to recognize and eliminate cancer cells.

Tumor cells hijack this mechanism by inducing Lose isoforms in surrounding microenvironment cells, allowing the cancer to thrive. While the role of Flower proteins in cell competition has been ...

Engineered immune cells called CAR-T cells are used in the treatment of cancer. Researchers from Uppsala University have now ...

“Traditional therapies target one molecule in the tumor microenvironment, but the microenvironment is so complex, targeting one thing doesn’t always work,” said Sidi Chen, an associate professor of ...

An immuno-oncology targeting panel accurately characterized tumor-resident immune cells and located pathologically and clinically relevant tumor microenvironment features. Cancer development and ...

Pan-cancer analyses of LongHorn-predicted lncRNA regulatory interactions suggest that the dysregulation of hundreds of lncRNAs target and alter the expression of cancer genes and pathways in each ...

Dr. Won Jin Ho presented a talk as part of the Immunology Neighborhood Seminar on “Overcoming the tumor immune ...