Scientists have supercharged CAR-T therapy, making it more powerful against elusive cancer cells that usually escape ...

Based on early studies, it was hypothesized that expression of Fas ligand (FasL) by tumor cells enabled them to counterattack the immune system, and that transplant rejection could be prevented by ...

Immunotherapy is based on harnessing a person's own immune system to attack cancer cells. However, patients with certain tumors do not respond to these therapies and it remains unclear why.

FBP1 helps activate tumor-suppressing mechanisms. However, the team found that most liver cancers in their study had developed ways to suppress FBP1, allowing precancerous cells to escape ...

the therapeutic becomes broadly applicable and “able to overcome common cancer escape pathways, including antigen loss,” Deban elaborates. In preclinical studies, Prokarium’s Living Cures ...

“Cancer cells are known for their ability to develop alternative protective pathways that allow them to survive exposure to agents that interrupt signaling cascades,” Grant said. “If one can identify ...

Cancers used to be defined by where they grow in the body—lung cancer, skin cancer, brain cancer, etc. But work in recent decades has shown that cancers sharing specific genetic changes may have more ...