MedPage Today on MSN7d
Trial Data Shed Light on ALS Clinical Research
The phase III trial COURAGE-ALS of investigational reldesemtiv, a fast skeletal troponin activator, did not meet its primary ...
Nature7y
Troponin and tropomyosin regulate contraction via calcium binding
Troponin is shown in red (subunits not distinguished). Upon binding calcium, troponin moves tropomyosin away from the myosin-binding sites on actin (bottom), effectively unblocking it. Modified ...