Removing EPO signaling in mouse liver tumors leads to tumor regression along with sensitivity to immunotherapy.

In the arthritic environment, Treg cells exhibit altered metabolic activity, reduced suppressive function, and increased PD-1 ...

Seismic Therapeutic has dosed the first healthy participant cohort in the randomised Phase I trial of bifunctional antibody S-4321.

Merck & Co/MSD has agreed to buy Pandion for $1.85 billion, bolting on a pipeline ... treating disease by modifying the activity of regulatory T cells, or Tregs. Pandion’s lead candidate PT101 ...

GLP-1RAs also exhibit several immune-modulating effects, with myeloid cells and regulatory subsets, such as Tregs, expressing a large concentration of GLP-1 receptors. Although increased Treg ...