Objective: To compare the 24-hour sustained efficacy and safety of a new tramadol once-daily formulation (tramadol OAD) using Contramid ® controlled-release technology with a marketed twice-daily ...
Background Tramadol is a synthetic opioid not banned by WADA, but included in the Monitoring Program since 2012. The prevalence of use of tramadol in competition was approximately 5% in cycling. These ...