The REVERSE-IT trial showed bentracimab effectively reversed the effects of ticagrelor, restoring platelet function with ...

The patients' average age was 65 years, 79.2% were men, and 76.1% were white. Most (75.7%) had high blood pressure, 74.3% had had a prior heart attack, 41.6% had diabetes and most were overweight ...

Bentracimab effectively reversed ticagrelor's antiplatelet effects, restoring platelet function in minutes for most patients in urgent situations. The REVERSE-IT trial showed 94.3% of patients ...

An investigational monoclonal antibody called bentracimab can safely and effectively reverse potentially catastrophic bleeding complications linked to ticagrelor, a common drug used to treat patients ...

A drug developed as an antidote to the antiplatelet agent ticagrelor safely and effectively reversed ticagrelor's antiplatelet effects in patients undergoing urgent surgery or experiencing major ...

We sought to compare the effectiveness and safety of acetylsalicylic acid (ASA) and ticagrelor or clopidogrel in patients with acute coronary syndrome from a single tertiary academic centre in ...

The results of PLATO (A Study of Platelet Inhibition and Patient Outcomes) 1 provide a major advance in our understanding of ADP receptor inhibition with the novel agent ticagrelor. When compared ...

Ticagrelor has saved the lives of thousands of heart attack patients around the world. Its journey from discovery over twenty years ago to world-wide treatment was the product of one of the largest ...

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A drug developed as an antidote to the antiplatelet agent ticagrelor safely and effectively reversed ticagrelor’s antiplatelet effects in patients undergoing urgent surgery or experiencing major ...

"The antidote, bentracimab, rapidly restored normal platelet function in ticagrelor-treated patients," said Deepak L. Bhatt, MD, MPH, MBA, director of the Mount Sinai Fuster Heart Hospital, the Dr ...