VD inhibits the polarization of naive T0 cells to T1 and to a lesser extent T2 cells (5.1.), it shifts the balance of Th1/Th2 T cells toward the latter ones (5.2.) and upregulates Treg cells ...

In this model, Th1 cells play a major role, while autoantibody production is a side effect with no pathogenic relevance. The decrease in Treg activity is probably one of the main mechanisms at the ...

T cells, with subsets like Th1, Th2, and Treg, are influenced by ferroptosis. In tumor microenvironments, tumor cells induce T cell ferroptosis via CD36 expression and lipid ROS accumulation ...