T cells may be broadly classified as either helper T cells (Th cells, CD4+) or cytotoxic T cells (Tc cells, CD8+). In 1986, T.R. Mosmann, R.L. Coffman, and colleagues observed that individual clones ...

The human body usually has a strong defense against viral infections, primarily through the rapid production of anti-viral T cells. Specifically, when a virus is detected, T Helper 1 (Th1 ...

Suppression of Th1 functions should shift the balance of Th1 versus Th2-mediated functions toward the Th2 cells. [50] Thus, VD should aggravate the Th2-mediated atopic diseases but in clinical ...

A new review was published as the cover paper of Aging, titled "Types of cell death and their relations to host immunological pathways." Various immune pathways in the host, such as TH1 ...

Our focus is on elucidating the mechanisms of DC-specific AIMp1 regulation of Th1 polarization. Dendritic cell vaccines can be generated via ex vivo differentiation followed by loading of MHC ...