The T follicular helper (Tfh) cells are a specialized subset of CD4+ T cells essential for the survival, affinity maturation, and class switch recombination of B cells. They promote effective B-cell ...

Kinetic analyses revealed that influenza nucleoprotein (NP)-specific BRMs differentiated early after infection and required T follicular helper (Tfh) cell help. BRM differentiation coincided with ...

One of the major research projects in the Hu laboratory is to study Tfh cell differentiation and germinal center (GC) responses. The humoral immune response is one of the two effector arms of the ...

More information: Saumya Kumar et al, Specialized Tfh cell subsets driving type-1 and type-2 humoral responses in lymphoid tissue, Cell Discovery (2024). DOI: 10.1038/s41421-024-00681-0 Provided ...