The researchers have additionally found new biomarkers that indicate the presence of a 4-repeat tauopathy. "Diagnosis gets really effective when we analyze a combination of cerebrospinal fluid ...

A few such syndromes that are well described and, like PD, are thought to be related to the abnormal accumulation of proteins such as alpha-synuclein (“synucleinopathy”) or tau (“tauopathy”). The ...

Space, An Early Frontier. When a brain region is tau-negative by SUVR (green arrow, left), spatial extent (dark blue) correlates better with measures of disease severity than does SUVR (light blue).

Early work revealed that TFEB is highly effective in ameliorating tau/NFT pathology and rescuing cognitive impairment and neurodegeneration. TFEB targets only the aberrant tau species and this ...