One of these evasion methods involves the production of thromboxane A2 (TXA2) by blood platelets, which suppresses the ...

Platelets release a molecule called thromboxane A2 (TXA2), which shuts down T cell activity, making it easier for cancer to ...

They followed signals inside the cell and found that a protein called ARHGEF1 gets activated when immune cells (T cells) come into contact with a clotting factor called thromboxane A2 (TXA2).

Researchers found that aspirin decreases thromboxane A2 (TXA2) production, thus preventing T cell suppression and reducing the frequency of metastases in mice models. This discovery suggests a ...

They found that ARHGEF1 is switched on when T cells are exposed to a clotting factor called thromboxane A2 (TXA2) – an unexpected finding for the scientists. TXA2 is produced by platelets in the ...