Tumor Necrosis Factor-alpha (TNF-α) is a cytokine important in nearly all acute inflammatory reactions by acting as an amplifier of inflammation. TNF-α blockade has been used worldwide to treat ...

is a member of the TNF superfamily of structurally related cytokines. It is present on the cell surface but a soluble form can also be produced by proteolytic cleavage within the stalk domain.

Sanofi’s development of an oral spin on Humira’s mechanism has hit a setback. | Sanofi’s development of an oral spin on ...

Ongoing projects: Study the effects of various neurotransmitters on the release of the cytokine TNF produced by macrophages, immune effector cells. Receptors on macrophages will be stimulated to ...

Cite this: TNF-α-induced Up-regulation of Pro-inflammatory Cytokines Is Reduced by Phosphatidylcholine in Intestinal Epithelial Cells - Medscape - Jul 13, 2009. 1 Department of Gastroenterology ...

The AI and machine learning technology of Renova Health, which comprises natural language processing (NLP) and a large ...

Image Credit: Sino Biological Inc. Disturbance in levels of the key pro-inflammatory cytokines, such as IL-6, IL-1β, and TNF-α, and anti-inflammatory cytokines, such as IL-10, IL-4, and TGF-β ...

Each works by preventing a particular cytokine from causing inflammation. Tumor Necrosis Factor, or TNF, occurs naturally in the body. It has been called the body's fire alarm because of its role ...