They discovered that the Toll-Like Receptor 9 (TLR9) inflammatory pathway was highly activated in these neurons. This pathway is typically involved in the immune response, detecting DNA fragments ...

with the colocalization of DNA fragments and TLR9 shown in orange, activating a cell signaling pathway that promotes the removal of self-reactive B cells. But, when CXCL4 levels are elevated ...

Patients with systemic lupus erythematosus (SLE) often require pulsed intravenous glucocorticoid therapy if oral glucocorticoids fail to control their disease. Why are doses of steroids that ...