Image Caption: TGF-β/Smad signaling pathway and miRNA regulation in liver fibrosis. Tissue fibrosis intricately links with the TGF-β/Smad signaling pathway. Ultimately, the findings underscore ...

Smad proteins mediate the transforming growth factor β responses. C-terminal phosphorylation of R-Smads leads to the recruitment of Smad4 and the formation of active signaling complexes.

a small molecule that occupies specifically the SMAD binding site in ACVR1, suppressed BMP-9-induced FOP-iMSC proliferation despite having no effects on TGF-β-induced proliferation of FOP- and ...

A new review published in Genes & Diseases highlights the transformative role of microRNAs (miRNAs) in regulating and ...