Iron-dependent ferroptosis, a non-apoptotic cell death mechanism, is gaining attention for its role in immune suppression. Ferroptosis, driven by excessive lipid peroxides and iron-dependent ...

Ferroptosis is a form of programmed cell death, distinct from apoptosis, that was identified in 2012. The process is driven by the iron-dependent oxidative degeneration of lipids. Image Credit ...

In a recent review published in the Cell Death Discovery Journal, researchers explored the association between ferroptosis and male reproductive failure, emphasizing the need for tailored ...

This graphical abstract shows how T-cells alter the metabolism of amino acids to cause ferroptosis. [University of Michigan Rogel Cancer Center] “Cancer immunotherapy restores or enhances the ...

Ferroptosis has garnered strong interest due to its therapeutic potential in addressing therapy-resistant and metastasizing cancers, and its involvement in neurodegenerative diseases.

Researchers report on a newly discovered biochemical pathway that protects cells from a type of cell death called ferroptosis. The hallmarks of cancer include rapid cell reproduction and metabolic ...

Patrizia Agostinis (VIB-KU Leuven) has found that melanoma cell populations protect themselves from a form of cell death called ferroptosis by secreting the lipoprotein apolipoprotein E (ApoE).