These discoveries raised the issue of whether the TCR repertoire underwent selection in each organism to most efficiently recognize antigens in the context of self MHC molecules at a time when it ...
The diversity of the TCR repertoire, however, means that sequencing is technically challenging, particularly for samples with low-quality, degraded nucleic acids. Current methods have significant ...
Marengo Therapeutics, Inc., a clinical-stage biotechnology company pioneering novel approaches for precision immunotherapy in oncology and autoimmune diseases, will present updated clinical and ...
Hosted on MSN11mon
Repertoire and Bristol Myers Squibb link on autoimmune disease vaccinesRepertoire Immune Medicines has collaborated ... The company will utilise its DECODE T cell receptor (TCR)-epitope discovery platform and lipid nanoparticle delivery technology to develop the ...
Hosted on MSN1mon
Machine learning tool decodes immune receptor sequences to diagnose multiple diseasesPaired BCR and TCR data were available for 542 individuals ... Mal-ID uses three models per receptor type: 1) repertoire composition assessing gene segment usage and somatic hypermutation rates ...
Cellecta, Inc. today announced the launch of the DriverMap™ Adaptive Immune Receptor (AIR) TCR and BCR kits, a family of multiplex-PCR, NGS-based assays that enable profiling of up to all seven T-cell ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback