TCR-peptide–MHC (pMHC) class I complexes for which crystal structures have been determined (mouse 2, 2C–dEV8–H-2K b, human 3,4: A6–Tax–HLA-A2 and B7–Tax–HLA-A2) indicate a common ...

Containing mutations in the MHC α3 domain that ablate CD8 binding; can be used to quantitate and to sort CD8-independent T cells. Developing high-affinity soluble antibody molecules endowed with a TCR ...

A bold funding initiative aims to help scientists predict a T cell’s target antigens, with implications far beyond cancer ...

Recently, the research team led by Professor Zhang Zhongtao and Professor Yao Hongwei from the General Surgery Center at Beijing Friendship Hospital, Capital Medical University, published a review ...