New research from the Kennedy Institute has revealed how two important proteins, TBK1 and IKKε, play a crucial role in preventing premature cell death, which can lead to serious inflammation in the ...

Ishii and colleagues now reveal that TBK1 (TANK-binding kinase 1) mediates the adjuvant effect of DNA vaccines and that this effect occurs independently of the TLR (Toll-like receptor) signalling ...

View Full Profile. Learn about our Editorial Policies. When STING is triggered, TANK-binding kinase (TBK1) activates and leads to interferon production. However, Tan and his team wanted to identify ...