The experiment involved replacing the Sox2 gene in mouse cells with the equivalent gene found in choanoflagellates. This ...

So, scientists must choose their targets very carefully. One promising target is a gene called SOX2. It helps control the behavior of stem cells and is crucial in early development. In normal ...

In a nutshell Scientists discovered that changing stem cells’ energy source from glucose to galactose creates “super stem ...

Tel Aviv University researchers used CRISPR to cut the SOX2 gene from head and neck cancer cells, eliminating 50% of tumors in mice. The study, published in Advanced Science, highlights CRISPR’s ...

with distinct gene expression patterns characterizing the proximal (closer to the trachea) and distal (toward the alveoli) regions. Genes such as Sox2 and Foxj1 are enriched in the proximal ...

Currently, the method is based on the combination of the four "Yamanaka factors" (OCT4, SOX2, KLF4 and C-MYC). We are using Sendai viruses to reprogram blood cells. We can reprogram fibroblasts using ...