But the new research indicates that their benefits may go much further. Some seem to activate a family of enzymes, sirtuins, known to extend the life span of yeast and laboratory worms living on a ...

These findings will be published soon, and are the latest in a series of discoveries Pernodet’s team has made about the role of sirtuins in the biology of the skin, and how they might be ...

Additionally, two groups of enzymes depend on NAD+ for their synthesis. These enzyme families, sirtuins (SIRTs) and poly(ADP-ribose) polymerases (PARPs), regulate numerous cellular activities ...