Autologous stem cell transplant for patients with diffuse systemic sclerosis (SSc), without selecting for a particular hematopoietic cell type, performed about as well in a new single-arm trial as ...

An innovative treatment could one day help restore fertility in men who do not have the capability to produce sperm, such as cancer survivors or those with certain genetic disorders. Scientists ...

As an orally available inhibitor of endothelin-1, which has been implicated in the pathogenesis of vascular disease in systemic sclerosis (SSc), bosentan is widely used as first-line therapy for ...

There are many aspects of SSc that support the hypothesis that it is an immune-mediated disease and might therefore respond to immunosuppressive therapy. [3] It is therefore relevant and timely to ...