Studies of chimeric antigen receptor (CAR) T-cell therapies have shown promise in SLE and lupus nephritis (LN) lately. According to GlobalData’s Pharmaceutical Intelligence Centre, there are 38 ...

Patients with SLE are known to have an increased risk of developing lymphomas. However, most of these lymphomas are of B-cell origin, in contrast to the T-cell lymphoma that developed in the ...

The U.S. Food and Drug Administration has granted regenerative medicine advanced therapy (RMAT) designation to Fate's FT819 ...

Singer Halsey is opening up about her battle with lupus SLE and a rare T-cell lymphoproliferative disorder after hinting about her illness in her newest song, "The End." In an Instagram post ...

USC researchers have developed an innovative type of cancer-fighting immune cell, the EchoBack CAR T-cell, that uses focused ...

Recent innovations include engineering CAR T-cells to overcome the immunosuppressive tumour microenvironment and enhancing their ability to infiltrate solid tumours.

where they stimulate naive and antigen-specific T cells as well as other effector cells. Circulating DCs are decreased in SLE; this is thought to be due to enhanced migration into peripheral ...

The Lupus Research Alliance (LRA) is proud to announce the recipients of this year’s Lupus Innovation Award (LIA), addressing many critical themes in lupus research including novel therapeutic ...

Optimal immune function necessitates a tight balance of the signaling pathways in both T- and B-cell compartments; these pathways are altered in both compartments in SLE and other autoimmune diseases.