Caption Model of recurrent type I IFN production in SLE patients: Double-stranded DNA in AdMVs stimulate the cGAS-STING signaling pathway in macrophages and non-hematopoietic cells, leading to ...

Zhijian “James” Chen, a biochemist at the University of Texas Southwestern Medical Center, was awarded the 2024 Albert Lasker Basic Medical Research Award for the discovery of the cGAS enzyme that ...